Mac’s October Goals
This month I have two goals directly related to methylation analysis. The first is to develop robust methods of analysis for MS-AFLP data using GeneMapper. The second is to get a really cool data set together to analyze the MBD-BS-Seq data in my Multivariate Statistics class. My hope is that by characterizing where the methylation is in the genome(e.g. exons, introns, gene boundaries, TE’s, long genes with introns, short genes with introns… yep, I could keep going here..), it will tell us something about the function of methylation (e.g. repression of TE’s, regulation of alternative splicing, etc.).
In addition, I plan on getting a final dissertation proposal approved by my committee so that I can schedule my general exam for November (barring any tragic outcomes of my qualifying exams - fingers crossed). My final goal for October is to get the FISH441 students ridiculously excited about using molecular methods to investigate response to environmental change in shellfish.